Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

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Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

Pepsinogen A (PGA) isozymogen patterns in urine and gastric mucosa can be visualised in non-denatured polyacrylamide gel electrophoresis by showing proteolytic activity after the conversion of pepsinogen into pepsin by acid. This method is not suitable for visualising PGA patterns in serum due to low PGA concentrations. To obtain a more sensitive visualisation method an immunoblotting technique...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1990

ISSN: 0021-9746

DOI: 10.1136/jcp.43.10.871