Immuno-pharmacokinetics of Meglumine Antimoniate in Patients With Cutaneous Leishmaniasis Caused by Leishmania (Viannia)
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چکیده
منابع مشابه
Cutaneous leishmaniasis caused by Leishmania (Viannia) panamensis in 2 travelers
PCR: polymerase chain reaction INTRODUCTION Leishmaniasis is an infectious disease endemic to 88 countries on 5 continents. It is estimated that there are 1 to 1.5 million cases of cutaneous leishmaniasis among local populations, but leishmaniasis also commonly affects travelers to these endemic countries. Leishmaniasis is caused by parasitic protozoa in the genus Leishmania, which are transmit...
متن کاملDetection of Leishmania in unaffected mucosal tissues of patients with cutaneous leishmaniasis caused by Leishmania (Viannia) species.
BACKGROUND Leishmania (Viannia) species are the principal cause of mucosal leishmaniasis. The natural history and pathogenesis of mucosal disease are enigmatic. Parasitological evaluation of mucosal tissues has been constrained by the invasiveness of conventional sampling methods. METHODS We evaluated the presence of Leishmania in the mucosa of 26 patients with cutaneous leishmaniasis and 2 p...
متن کاملComparison of meglumine antimoniate and pentamidine for peruvian cutaneous leishmaniasis.
Pentamidine was compared with meglumine antimoniate (Glucantime) for 80 patients with cutaneous leishmaniasis due to Leishmania braziliensis in Peru. Of the 40 patients administered Glucantime (20 mg of antimony [Sb]/kg/day intravenously for 20 days), 31 cured (78%), 6 failed (15%), of which 5 were due to relapse, and 3 were lost to follow-up (7%). Of the 40 patients administered pentamidine (2...
متن کاملGenotypic profiles of Leishmania (Viannia) braziliensis strains from cutaneous leishmaniasis patients and their relationship with the response to meglumine antimoniate treatment: a pilot study
BACKGROUND Forty-four strains isolated from a cohort of cutaneous leishmaniasis (CL) patients who did or did not respond to one course of treatment with meglumine antimoniate were investigated to explore genetic polymorphisms in parasite kinetoplast DNA minicircles. Leishmania (Viannia) braziliensis strains isolated from responder (R) and non-responder (NR) patients who acquired infection in Ri...
متن کاملMucosal Leishmaniasis Caused by Leishmania (Viannia) braziliensis and Leishmania (Viannia) guyanensis in the Brazilian Amazon
BACKGROUND Leishmania (Viannia) braziliensis is a parasite recognized as the most important etiologic agent of mucosal leishmaniasis (ML) in the New World. In Amazonia, seven different species of Leishmania, etiologic agents of human Cutaneous Leishmaniasis, have been described. Isolated cases of ML have been described for several different species of Leishmania: L. (V.) panamensis, L. (V.) guy...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2020
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/ciaa1206