Immunity improvement and gut microbiota remodeling of mice by wheat germ globulin

Immunity, gut microbiota and infection

Recurrent infections are very common in children and a major challenge for pediatricians. They affect the children’s quality of life, cause absences from school and lost parental working days, and repeated medical examinations, hospital admissions as well as antibiotic therapies lead to high costs for society. Given their prevalence and clinical importance, various prevention strategies have be...

Perinatal programming of gut microbiota and immunity.

High frequencies of antibiotic resistance genes in infants’ meconium and early fecal samples M. J. Gosalbes and Y. Vallès and N. Jiménez-Hernández and C. Balle and P. Riva and S. Miravet-Verde and L. E. de Vries and S. Llop and Y. Agersø and S. J. Sørensen and F. Ballester and M. P. Francino Journal of Developmental Origins of Health and Disease, Volume 7, Issue 01, February 2016, pp 35-44 doi:...

Gut Microbiota and Neuropsychiatric Disorders

Intestinal Immunity and Gut Microbiota in Atherogenesis

Atherosclerosis is a chronic inflammatory disease. Interventions targeting the inflammatory process could provide new strategies for preventing atherosclerotic cardiovascular diseases (CVD). Previously, we have reported that oral administration of anti-CD3 antibodies, or active vitamin D3, reduced atherosclerosis in mice via recruiting regulatory T cells and tolerogenic dendritic cells to the g...

Alterations in Gut Microbiota and Immunity by Dietary Fat

Gut microbiota play critical physiological roles in energy extraction from the intestine and in the control of systemic immunity, as well as local intestinal immunity. Disturbance of gut microbiota leads to the development of several diseases, such as colitis, inflammatory bowel diseases, metabolic disorders, cancer, etc. From a metabolic point of view, the gut is a large metabolic organ and on...