Immune complex–mediated antigen presentation induces tumor immunity
نویسندگان
چکیده
منابع مشابه
Immune complex-mediated antigen presentation induces tumor immunity.
Antigen uptake receptors on dendritic cells (DCs) provide efficient entry for the initiation of antigen-specific adaptive immunity. Here we show that targeting of antigen to Fc receptors on DCs accomplishes combined activation of Th1 CD4 and CD8 effector responses in vivo, namely delayed-type hypersensitivity and tumor immunity. Tumor immunity specific for ovalbumin-expressing tumors was provid...
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Matthew D. Griffin1, Nianzeng Xing1,3, and Rajiv Kumar1,2 1Department of Internal Medicine, Division of Nephrology, and 2Department of Biochemistry and Molecular Biology and Mayo Proteomics Research Center, Mayo Clinic and Foundation, Rochester, Minnesota 55905; email: [email protected]; [email protected]; [email protected] 3Current address: Department of Urology, Beijing Chao Yang Ho...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2002
ISSN: 0021-9738
DOI: 10.1172/jci0215640