Immune Complex Diseases
نویسندگان
چکیده
منابع مشابه
Rheumatoid arthritis and systemic lupus erythematosus as immune complex diseases.
Rheumatoid factors are 9s IgM autoantibodies directed against the hinge regions of 7s IgG's that have been changed consequent to their encounter with a foreign antigen, such as those produced by oral bacteria. Occasionally self-aggregating 7s IgG's serve this function. When these complexes are taken up by phagocytes in the joint, they form the "RA cell," a cell analogous to the LE cell of Hargr...
متن کاملA full complement of receptors in immune complex diseases.
In this issue of the JCI, Shushakova et al. (1) describe experimental results that provide a direct link between the C5a anaphylotoxin and the IgG Fc receptors (FcγRs) in mediating immune complex–triggered (IC-triggered) inflammatory disease. Using a murine lung model of IC-induced inflammation, the authors demonstrate that C5a, acting through the C5a receptor (C5aR), exacerbates inflammation i...
متن کاملImmune deficiency diseases.
Paediatricians have long been deeply concerned with problems of infection. The sharp decrease in childhood mortality in recent decades in highly developed countries is mainly due to progress in preventing and treating infection: for example, in Switzerland in 1973 there were about 88 000 births and only 16 deaths due to infection in children aged between 2 and 4 years in contrast to 76 killed b...
متن کاملVitiligo and auto immune diseases: A survey of 100 patients
Vitiligo is an autoimmune skin disease which is characterized by depigmented patches due to loss of pigment cells. Evidence suggests that cell-mediated immunity plays a role in melanocyte destruction while some patients have antibodies to melanocytes or melanocytic proteins. Vitiligo is strongly associated with a number of autoimmune disorders. Autoimmune thyroiditis is the most prevalent disea...
متن کاملComplex diseases require complex therapies.
Since the rise of modern pharmaceuti cal research and industry in the 1950s, drugs have been used to treat an increasingly wide range of diseases. From antibiotics for treating infections, to anti virals to treat HIV/AIDS, to drugs for hyper tension and cancer, drugbased therapies have had enormous effects in curing or con verting often fatal diseases into manageable conditions. Even patho...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1972
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12627589