IMMENSE DOSES OF OPIATES.

The immense potential of xenotransplantation in surgery.

There is a limited availability of deceased human organs and cells for the purposes of clinical transplantation. Genetically-engineered pigs may provide an alternative source. Although several immune barriers need to be overcome, considerable progress has been made in experimental models in recent years, largely through the increasing availability of pigs with new genetic modifications. Pig het...

Opiates and plasticity.

Opiates are among the most powerful analgesics and pain-relieving agents. However, they are potentially extremely addictive thereby limiting their medical use, making them exceedingly susceptible to abuse and adding to the global drug problem. It is believed that positive memories associated with the pleasurable effects of opiates and negative memories associated with dysphoria during opiate wi...

Cancer-related fatigue: An immense problem.

Exercise and Endogenous Opiates

Overdosing on opiates

Essential practice points from this article Part I of this article ( issue 4) identified the things drug users and others do or don’t do which affect the risk of overdose, and the influences which make these behaviours more or less likely. Key conclusion: overdose deaths are avoidable: rarely is taking heroin or taking a high dose the sole cause. Other factors turn potential risk into reality, ...