Imaging‐Guided Targeted Drug Delivery using Stimuli‐Sensitive Theranostic Nanoparticles: Characterization and In Vivo Trafficking Patterns

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Multifunctional MIL-S─CUR@FC nanoparticles: a targeted theranostic agent for magnetic resonance imaging and tumor targeted delivery of curcumin

Introduction: Noninvasive magnetic resonance imaging (MRI) and targeted drug delivery systems, usually referred to as theranostic agents, are being developed to enable detection, site-specific treatment, and long-term monitoring.   Materials and Methods: To elucidate the effects of coating on cellular uptake and biodistribution of n...

Tumor Penetrating Theranostic Nanoparticles for Enhancement of Targeted and Image-guided Drug Delivery into Peritoneal Tumors following Intraperitoneal Delivery

The major obstacles in intraperitoneal (i.p.) chemotherapy of peritoneal tumors are fast absorption of drugs into the blood circulation, local and systemic toxicities, inadequate drug penetration into large tumors, and drug resistance. Targeted theranostic nanoparticles offer an opportunity to enhance the efficacy of i.p. therapy by increasing intratumoral drug delivery to overcome resistance, ...

Docetaxel delivery using folate-targeted liposomes: in vitro and in vivo studies

Objective(s): Folate-targeted liposomes have been well considered in folate receptor (FR) overexpressing cells including MCF-7 and 4T1 cells in vitro and in vivo. The objective of this study is to design an optimum folate targeted liposomal formulations which show the best liposome cell uptake to tumor cells.Material and Methods: In this study, we prepared and characterized different targ...