Imaging techniques for assaying lymphocyte activation in action

Imaging techniques in dermatology

Since the discovery of X-rays, the use of imaging technology has continued to play an important role in medicine. Technological advancements have led to the development of various imaging modalities, most of which have been used to image organs deep within the human body. More recently, attention has focused on the application of imaging technology for evaluation of the skin. A variety of techn...

Microfluidic single-cell technologies for assaying lymphocyte interactions

magnetic resonance imaging in dentistry

چکیده ندارد.

Mechanosensing in T lymphocyte activation.

Mechanical forces play an increasingly recognized role in modulating cell function. This report demonstrates mechanosensing by T cells, using polyacrylamide gels presenting ligands to CD3 and CD28. Naive CD4 T cells exhibited stronger activation, as measured by attachment and secretion of IL-2, with increasing substrate elastic modulus over the range of 10-200 kPa. By presenting these ligands o...

Mechanisms of Lymphocyte Activation

The interactions of phytohemagglutinin (PHA) with normal human lymphocytes were studied utilizing radioiodinated leukoagglutinin (“$I-LPHA) over a concentration spectrum encompassing the entire range of lymphocyte metabolic responses. “jI-LPHA binding was temperature-, pH-, and time-dependent. Ligand association was rapid with at,,* of 3 to 5 min, reaching steady state in 30 min at 22”. Recepto...