Ilae classification of seizures and antiepileptic medications apothegmatic: hereafter advancement and clinical practice

Introduction: The Antiepileptic medications are frequently categorized into divisions such as ‘first-generation’ (i.e., carbamazepine, phenobarbital, phenytoin, primidone, and valproate) ‘second-generation’ (lamotrigine, levetiracetam, felbamate, gabapentin, topiramate, tiagabine, oxycarbazepine, zonisamide, pregabalin). Chronic phenytoin ingestion leads to its impact in the cerebral cortex, resulting atrophy of cerebellum, cause ataxia nystagmus. Objective: To recapitulate International league against epilepsy classifications, first treatment for based on their antiepileptic adverse drug reaction, Methodology: author used 74 distinctive published articles accomplishment this review article. Google search engine was accessing from databases like Scholar, Research Gate, PubMed, NCBI, NDSS, PMID, PMCID, Cochrane Database CLINMED international library. Findings: Tonic-clonic is characterized by stiffness loss consciousness occurred tonic extension rhythmic clonic contractions all considerable muscle groups. drugs implicitly an effective patient with epilepsy. Carbamazepine serious sometimes fatal dermatologic reactions, including toxic epidermal necrolysis stevens-johnson syndrome, aplastic anemia agranulocytosis, Suicidal Behavior Ideation, Stevens johnson cholestatic jaundice, ataxia, xerostomia, speech disturbances, feeling sleepy Conclusion: Commonly happening side-effects AEDs memory troubles, exhaustion, tremors, gastrointestinal symptoms, osteoporosis, depression, drowsiness, dizziness, weight change, nausea. In generalized seizures, other hand, seizure endeavor primary seizures), launching both hemispheres brain contemporaneously