<i>Lacticaseibacillus rhamnosus</i> Probio-M9 may be vertically transmitted from mother to infant during lactation based on faeces metagenomics

Probiotics exert beneficial effects on the host. This study aimed to investigate whether maternally ingested Lacticaseibacillus rhamnosus Probio-M9 during pregnancy could access and colonize in infant gut. recruited one pregnant woman, who daily from 35 weeks of gestation delivery. Faeces mother-infant pair were regularly collected month before delivery six months infant's age for metagenomic sequencing. genomes mappable all faecal samples, suggesting probiotics be vertically transmitted mother infant. Infant- or mother-specific differential metabolic pathways found between maternal gut microbiome, implicating apparent differences intestinal potential/function In conclusion, ingestion final deliver The findings provided novel insights into shaping microbiota.