IL12Rβ1: The cytokine receptor that we used to know

How do we know that we know what we know?

How Science Works’ is now the focus of the national science specifications in English schools. This article is a brief introduction to the philosophy of science from the Greeks to the present day that underpins this notion. From September 2006, the emphasis for teaching science at GCSE is on ‘How Science Works’. This focus will also shape the revisions of the AS and A2 specifications from Septe...

Do We Know What We Do not Know? A Response to Celine Bonnet

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

What we know now that we didn't know then.

Superior Capsule Reconstruction: What Do We Know?

The management of irreparable rotator cuff tears remains challenging. Since its introduction by Mihata in 2012, superiorcapsule reconstruction (SCR) has grown in popularity at an astonishingly rapid rate. The aim of this article is to providea comprehensive review of the available literature, in order to highlight what has so far been published on SCR,covering all aspects including biomechanica...