IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis
نویسندگان
چکیده
منابع مشابه
IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis
BACKGROUND Methotrexate (MTX) is the standard first-line therapy in rheumatoid arthritis (RA) with variable clinical efficacy that is difficult to predict. The glycosylation status of immunoglobulin G (IgG) is altered in RA and influenced by MTX treatment. We aimed to further investigate if IgG glycosylation in untreated early RA can predict therapeutic response to MTX. METHODS We used a shot...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2017
ISSN: 1478-6362
DOI: 10.1186/s13075-017-1389-7