IGFBP2 is a biomarker for predicting longitudinal deterioration in renal function in type 2 diabetes

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IGFBP2 is a biomarker for predicting longitudinal deterioration in renal function in type 2 diabetes

OBJECTIVE Insulin-like growth factors are implicated in the development of diabetic nephropathy. IGF-binding protein 2 (IGFBP2) and IGF2 are expressed in the kidney, but their associations with diabetic nephropathy are unclear. We therefore tested the hypothesis that circulating levels of IGF2 and IGFBP2 predict longitudinal renal function in individuals with type 2 diabetes. DESIGN AND METHO...

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ژورنال

عنوان ژورنال: Endocrine Connections

سال: 2012

ISSN: 2049-3614

DOI: 10.1530/ec-12-0053