IFN-? limitin: a member of type I IFN with mild lympho-myelosuppression
نویسندگان
چکیده
منابع مشابه
Type I IFN protects against murine lupus.
Both the type I (IFN-alpha beta) and type II (IFN-gamma) IFNs have been heavily implicated in the pathogenesis of systemic lupus erythematosus. To test the relative roles of these systems, congenic lupus-prone MRL/CD95(lpr/lpr) (MRL/lpr) mice lacking the type I IFN receptor (IFN-RI), type II IFN receptor (IFN-RII), or both, were derived. As expected, deficiency for IFN-RII protected MRL/lpr mic...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2005
ISSN: 1582-1838,1582-4934
DOI: 10.1111/j.1582-4934.2005.tb00353.x