Identification of Two Novel Regulatory Elements in the IL2RA Gene Locus
نویسندگان
چکیده
منابع مشابه
Identification of Two Novel Mutations in KDM3A Regulatory Gene in Iranian Infertile Males
Background: KDM3A is a key epigenetic regulator that is expressed in the testis and is required for packaging and condensation of sperm chromatin. To this point, the association of the KDM3A gene and infertility has not been studied in human. The aim of this study was to screen any new mutation in KDM3A gene to explore more details of human male infertility. Methods: In this work, 150 infertile...
متن کاملA cis-acting regulatory variant in the IL2RA locus.
The mechanism for the association of type 1 diabetes (T1D) with IL2RA remains to be clarified. Neither of the two distinct, transmission-disequilibrium confirmed loci mapping to this gene can be explained by a coding variant. An effect on the levels of the soluble protein product sIL-2RA has been reported but its cause and relationship to disease risk is not clear. To look for an allelic effect...
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ژورنال
عنوان ژورنال: Journal of Pulmonary & Respiratory Medicine
سال: 2018
ISSN: 2161-105X
DOI: 10.4172/2161-105x.1000458