Identification of the equine herpesvirus type 1 glycoprotein 17/18 as a homologue of herpes simplex virus glycoprotein D

Immunogenicity and Efficacy of Baculovirus Derived Glycoprotein D of Herpes Simplex Virus Type-I in Mice

Characterization of an equine herpesvirus type 1 gene encoding a glycoprotein (gp13) with homology to herpes simplex virus glycoprotein C.

The molecular structure of the equine herpesvirus type 1 (EHV-1) gene encoding glycoprotein 13 (gp13) was analyzed. The gene is contained within a 1.8-kilobase AccI-EcoRI restriction fragment mapping at map coordinates 0.136 to 0.148 in the UL region of the EHV-1 genome and is transcribed from right to left. Determination of the nucleotide sequence of the DNA fragment revealed a complete transc...

A Preliminary Study on the Molecular Identification of Herpes Simplex Virus Type 1 in Iranian Population

Herpes Simplex Virus Type 1 (HSV-1) is a member of the Herpesviridae family that causes herpetic disease in human. During the last 25-30 years, many investigations have been conducted on pathogenesis and molecular biology of this virus in several countries. In Iran HSV-1 has been isolated from patients and detected using immunological techniques. In this study, we investigated the molecular asp...

immunogenicity and efficacy of baculovirus derived glycoprotein d of herpes simplex virus type-i in mice

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Characterization of a heparan sulfate octasaccharide that binds to herpes simplex virus type 1 glycoprotein D.

Herpes simplex virus type 1 utilizes cell surface heparan sulfate as receptors to infect target cells. The unique heparan sulfate saccharide sequence offers the binding site for viral envelope proteins and plays critical roles in assisting viral infections. A specific 3-O-sulfated heparan sulfate is known to facilitate the entry of herpes simplex virus 1 into cells. The 3-O-sulfated heparan sul...