Identification of quinolinic acid-utilizing bacteria.
نویسندگان
چکیده
منابع مشابه
Quinolinic Acid Metabolism
Since the observation (1) that tryptophan and nicotinic acid are mutually interchangeable, within limits, in supporting the growth of rats, considerable evidence has accumulated which indicates that biosynthesis of nicotinic acid can proceed from tryptophan (2-5). Unequivocal evidence for this transformation was provided by the experiments of Heidelberger et al. (6) who fed labeled tryptophan @...
متن کاملQuinolinic acid metabolism in the rat brain. Immunohistochemical identification of 3-hydroxyanthranilic acid oxygenase and quinolinic acid phosphoribosyltransferase in the hippocampal region.
Quinolinic acid (QUIN) is a potent endogenous excitotoxin, which has been shown to be present in the brain (Wolfensberger et al., 1983). In order to study the cellular localization of QUIN metabolism in the hippocampus, specific antibodies raised against purified rat liver 3-hydroxyanthranilic acid oxygenase (3HAO) and quinolinic acid phosphoribosyltransferase (QPRT), the enzymes directly respo...
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Differences in phospholipid and fatty acid composition were found among bacteria using the serine or the ribulose monophosphate pathway for the assimilation of C1 compounds. These differences might be used as an additional criterion for the classification of methanol-utilizing bacteria.
متن کاملQuinolinic acid excretion and metabolism in man.
In 1946, Rosen e2 al. (1) showed that administration of tryptophan to rats resulted in an additional excretion of nicotinic acid and Nl-methylnicotinamide (Nl-Me). Singal et al. (2) found, in addition to these, increased excretion of another metabolite which could be converted to nicotinic acid by autoclaving in 1 N sulfuric acid solution. Henderson isolated this metabolite from the urine of ra...
متن کاملMetabolism and neuropathologic significance of quinolinic acid and kynurenic acid.
Neurologic symptoms and neurodegeneration are important causes of morbidity and mortality in man. Although many pathogenic mechanisms could account for neurologic dysfunction, considerable interest has focused on a group of neurotoxins known as the ‘excitotoxins’. Quinolinic acid (QUIN) is an excitotoxic L-tryptophan and kynurenine pathway metabolite that is an agonist of N-methyl-uaspartate (N...
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ژورنال
عنوان ژورنال: The Journal of General and Applied Microbiology
سال: 1979
ISSN: 1349-8037,0022-1260
DOI: 10.2323/jgam.25.279