Identification of procalcitonin in a rat medullary thyroid carcinoma cell line.

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Identification of procalcitonin in a rat medullary thyroid carcinoma cell line.

As a first step in studying the biosynthesis of the peptide hormone calcitonin, we have identified procalcitonin species in CA-77 cells, a newly developed rat medullary thyroid carcinoma cell line. mRNA extracted from the cells directed the synthesis of a putative procalcitonin in a reticulocyte lysate translation system containing microsomal membranes. Both this species and a radiolabeled form...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1984

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(17)43228-5