Identification of miRNAs in cervical mucus as a novel diagnostic marker for cervical neoplasia

p16 as a diagnostic marker of cervical neoplasia: a tissue microarray study of 796 archival specimens

BACKGROUND To evaluate the usefulness of this biomarker in the diagnosis of cases of cervical neoplasia we studied the immunohistochemical expression of p16INK4a in a large series of archival cervical biopsies arranged into tissue microarray format. METHODS TMAs were constructed with tissue cores from archival formalin fixed, paraffin-embedded donor tissues from 796 patients, and included cas...

Molecular Identification of Human Papiloma Virus (HPV) in Cervical Neoplasia and the Risk Factors Affecting Cervical Cancer in Isfahan

The rate of cervical cancer in Asians is deferent, based on the risk factors affecting and the rate of papiloma virus infection among females. Cervical cancer is one of the important cancers between Iranian women. In the present study the rate of cervical neoplasia was detected in Isfahan and some risk factors affecting the incidence of cervical cancer was analyzed. The human papiloma virus inf...

University of Groningen Detection of DNA hypermethylation as a diagnostic tool in cervical neoplasma tool in cervical neoplasia

Accuracy of the peak day of cervical mucus as a biological marker of fertility.

The (PD) peak day of cervical mucus is an important biologic marker for the self-determination of the optimal time of fertility in a woman's menstrual cycle. The purpose of this article is to provide evidence (literature and empiric) for the accuracy of the PD of cervical mucus as a biologic marker of peak fertility and the estimated day of ovulation. An analysis of data from four published stu...

Molecular diagnostic assays for cervical neoplasia: emerging markers for the detection of high-grade cervical disease.

The accurate detection and diagnosis of cervical carcinoma and its malignant precursors (collectively referred to as high-grade cervical disease) represents one of the current challenges in clinical medicine and cytopathology. The advent of molecular diagnostics and the use of whole-genome profiling using DNA microarrays promises to yield improved understanding of the disease process with the s...