Identification of intracellular targets of small molecular weight chemical compounds using affinity chromatography
نویسندگان
چکیده
منابع مشابه
Identification of volatile organic compounds of some Trichoderma species using static headspace gas chromatography-mass spectrometry
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Preparation of Plasminogen by Affinity Chromatography
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Identification of the cellular targets of bioactive small organic molecules using affinity reagentsw
The elucidation of molecular targets of bioactive small organic molecules remains a significant challenge in modern biomedical research and drug discovery. This tutorial review summarizes strategies for the derivatization of bioactive small molecules and their use as affinity probes to identify cellular binding partners. Special emphasis is placed on logistical concerns as well as common proble...
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ژورنال
عنوان ژورنال: Biotechnology Journal
سال: 2007
ISSN: 1860-6768,1860-7314
DOI: 10.1002/biot.200600223