Identification of interleukin-6 (IL-6) and squamous cell carcinoma (SCC) as amniotic fluid-specific markers

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Identification of interleukin-6 (IL-6) and squamous cell carcinoma (SCC) as amniotic fluid-specific markers

Objective: To determine if an amniotic fluid (AF)specific marker is present and if its concentration changes with the presence of labor. Study Design: Twenty-six healthy women who gave birth to healthy newborns at term during the period from July 2009 to January 2010 were included in the study. Six candidate markers were assessed by commercially available ELISA kits: interleukin (IL)-6, squamou...

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Serum Level of Interleukin-6 in Patients with Oral Tongue Squamous cell Carcinoma

Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to investigate the serum le...

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Expression of CK8 and CK17, Specific Epithelial Markers, by Oral Squamous Cell Carcinoma Cell Lines

Objectives Oral squamous cell carcinoma (OSCC) is among the most common cancers worldwide. This study aimed to assess the expression of CK8 and CK17 by OSCC cell lines in Iranian patients. Methods This observational study was conducted on three OSCC cell lines with a minimum of 45 passages. Cells isolated from three patients with OSCC were cultured and passaged. Expression of CK8 and CK17 epi...

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Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma.

BACKGROUND Since morbidity and mortality rates due to oral cavity and oropharyngeal squamous cell carcinoma (OSCC) have improved little in the past 30 years, early detection or prevention of this disease is likely to be most effective. Using laser-capture microdissection, we have identified the expression of 2 cellular genes that are uniquely associated with OSCC: interleukin (IL) 6 and IL-8. T...

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Measurement of Amniotic Fluid Interleukin-6 Using Commercial Kits

OBJECTIVE The association between increased amniotic fluid interleukin-6 (IL-6) concentrations and preterm labor has received increasing attention. Several research groups have evaluated this association using commercial IL-6 kits, which principally use the sandwich-enzyme-immunoassay method, and were originally created to measure IL-6 in plasma, serum, or culture media. We evaluated commercial...

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ژورنال

عنوان ژورنال: Open Journal of Obstetrics and Gynecology

سال: 2012

ISSN: 2160-8792,2160-8806

DOI: 10.4236/ojog.2012.22028