Identification of glomerular immune deposits in cryoglobulinemia glomerulonephritis
نویسندگان
چکیده
منابع مشابه
Aberrantly glycosylated IgA1 in glomerular immune deposits of IgA nephropathy.
In IgA nephropathy, abnormal O-glycosylation of IgA1 molecules contributes to mesangial IgA1 deposition and the development of glomerular injury; however, direct in situ demonstration of aberrantly O-glycosylated IgA1 within glomerular immune deposits has not been reported. This study investigated the presence of abnormally glycosylated IgA1 in situ and its spatial relationship with complement ...
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A 15-year-old boy is admitted to the hospital for clinical signs that suggest a pulmonary-renal syndrome (fever, cough, hemopthoic expectoration, oliguria, gross hematuria). A crescentic pANCA positive glomerulonephritis was configured. However, dense subendothelial deposits were identified in electronic microscopy and immunofluorescence staining showed granular deposits of IgG and C3, kappa an...
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Six patients with coexistent antiglomerular basement membrane disease and granular immunoreactants in the glomerular basement membrane and mesangium are discussed. These six patients represent 35% of all patients with antiglomerular basement membrane nephritis examined over 10 years. All patients presented with acute, oliguric renal failure, and rapid deterioration in renal function. In all pat...
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Anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis is considered a "pauci-immune" disease, characterized by absent or mild glomerular tuft staining for immunoglobulin and/or complement. We describe a 72-year-old man with progressive renal failure over five months who was found to have P-ANCA associated crescentic glomerulonephritis. Renal biopsy also revealed immunofluore...
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Adult Paris R-III mice with localized mamary tumors were found to have subendothelial glomerular immune complex deposits by electron microscopy and immunofluorescence. In addition to IgG adn B-1-C, the glomeruli contained antigenic material that reacted with an antiserum to mouse mamary tumor virus. These findings support the hypothesis that many animals with congenitally or neonatally induced ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1988
ISSN: 0085-2538
DOI: 10.1038/ki.1988.152