Identification of discrete chromosomal deletion by binary recursive partitioning of microarray differential expression data
نویسندگان
چکیده
منابع مشابه
Identification of discrete chromosomal deletion by binary recursive partitioning of microarray differential expression data.
DNA copy number abnormalities (CNA) are characteristic of tumours, and are also found in association with congenital anomalies and mental retardation. The ultimate impact of copy number abnormalities is manifested by the altered expression of the encoded genes. We previously developed a statistical method for the detection of simple chromosomal amplification using microarray expression data. In...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 2005
ISSN: 1468-6244
DOI: 10.1136/jmg.2004.025353