Identification of circulatory biomarkers from clinical trial samples
نویسندگان
چکیده
منابع مشابه
Identification of circulatory biomarkers from clinical trial samples
Background Despite significant advances in genomics, proteomics and metabolomics, the identification and validation of circulatory immunological biomarkers in cancer patients, which could be useful to monitor disease progression and response to immunotherapeutic treatments, remains as elusive as ever. Circulatory biomarkers, being easily accessible, may provide crucial guidance and be incorpora...
متن کاملIdentification of non-tuberculous mycobacteria from clinical samples.
Non-tuberculous mycobacterial infections cause morbidity worldwide. NTM are considered opportunistic pathogens, and several species have been associated with human disease which has typically pulmonary, skin and soft tissue, lymphatic or disseminated presentation. This study evaluated the distribution of non-tuberculous mycobacteria in Sardinia. Mycobacterium avium, Mycobacterium gordonae and M...
متن کاملSubgroup identification from randomized clinical trial data.
We consider the problem of identifying a subgroup of patients who may have an enhanced treatment effect in a randomized clinical trial, and it is desirable that the subgroup be defined by a limited number of covariates. For this problem, the development of a standard, pre-determined strategy may help to avoid the well-known dangers of subgroup analysis. We present a method developed to find sub...
متن کاملThe identification of tuberculosis biomarkers in human urine samples.
We aimed to determine whether shotgun proteomic approaches could be used to identify tuberculosis (TB)-specific biomarkers in the urine of well-characterised patients with active TB versus no TB. Patients with suspected TB (n=63) were classified as: definite TB (Mycobacterium tuberculosis positive culture, n=21); presumed latent-TB infection (LTBI) (M. tuberculosis negative culture, no radiolog...
متن کاملBimolecular identification of M.ovinpeumoniae from nasal swab samples of sheep from various districts of Balochistan, Pakistan
Mycoplasma ovipneumoniae is an important respiratory pathogen of sheep across the world. In the present study nasal swab samples (n=778) were processed and 51isolates of M. ovipneumoniae were identified through biochemical tests and PCR. Difference in the isolation rate among districts (n=12), age groups (n=3), breads (n=6) was assessed. Similarly the isolate rate among healthy (n=513) and resp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal for ImmunoTherapy of Cancer
سال: 2015
ISSN: 2051-1426
DOI: 10.1186/2051-1426-3-s2-p104