Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration
نویسندگان
چکیده
منابع مشابه
Differential expression of FGF receptors during zebrafish fin regeneration
*Address correspondence to: Leonor Santos-Ruiz. Departamento de Biología Celular y Genética, Facultad de Ciencias, Universidad de Málaga, Spain. e-mail: [email protected] ABSTRACT Teleost fins can be structural and functionally restored after severe injuries or partial amputation through a process of epimorphic regeneration, which requires an acute temporal and spatial control of basic cell events...
متن کاملFgf and Sdf-1 Pathways Interact during Zebrafish Fin Regeneration
The chemokine stromal cell-derived factor-1 (SDF1) was originally identified as a pre-B cell stimulatory factor but has been recently implicated in several other key steps in differentiation and morphogenesis. In addition, SDF1 as well as FGF signalling pathways have recently been shown to be involved in the control of epimorphic regeneration. In this report, we address the question of a possib...
متن کاملRequirements for the kit receptor tyrosine kinase during regeneration of zebrafish fin melanocytes.
Embryonic neural crest-derived melanocytes and their precursors express the kit receptor tyrosine kinase and require its function for their migration and survival. However, mutations in kit also cause deficits in melanocytes that make up adult pigment patterns, including melanocytes that re-establish the zebrafish fin stripes during regeneration. As adult melanocytes in mice and zebrafish are g...
متن کاملTranscriptional components of anteroposterior positional information during zebrafish fin regeneration.
Many fish and salamander species regenerate amputated fins or limbs, restoring the size and shape of the original appendage. Regeneration requires that spared cells retain or recall information encoding pattern, a phenomenon termed positional memory. Few factors have been implicated in positional memory during vertebrate appendage regeneration. Here, we investigated potential regulators of ante...
متن کاملZebrafish ProVEGF-C Expression, Proteolytic Processing and Inhibitory Effect of Unprocessed ProVEGF-C during Fin Regeneration
BACKGROUND In zebrafish, vascular endothelial growth factor-C precursor (proVEGF-C) processing occurs within the dibasic motif HSIIRR(214) suggesting the involvement of one or more basic amino acid-specific proprotein convertases (PCs) in this process. In the present study, we examined zebrafish proVEGF-C expression and processing and the effect of unprocessed proVEGF-C on caudal fin regenerati...
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ژورنال
عنوان ژورنال: Development
سال: 2020
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.191262