Ideal Cardiovascular Health and Progression of CKD: Perhaps not so “Simple”

Asymptomatic hyperuricemia: perhaps not so benign?

High-dose statin, not so IDEAL?

Tikkanen et al. (1) present an interesting post-hoc analysis of the IDEAL (Incremental Decrease in Endpoints Through Aggressive Lipid Lowering) study with a novel statistical method using all vascular rather than just the first cardiovascular events recorded, and they propose highly significant p values in support of using top-dose atorvastatin (80 mg/day) versus "standard" dose simvastatin (20...

Matching taxpayer funding to population health needs: not so simple.

Serum Creatinine: Not So Simple!

Measuring serum creatinine is cheap and commonly done in daily practice. However, interpretation of serum creatinine results is not always easy. In this review, we will briefly remind the physiological limitations of serum creatinine due notably to its tubular secretion and the influence of muscular mass or protein intake on its concentration. We mainly focus on the analytical limitations of se...

Not so simple renal cysts

An 82-year-old male had been suffering from anorexia and abdominal discomfort for several months. He was admitted to hospital, incapable of walking due to a prominent abdomen. His medical history showed hypertension for 10 years and renal cysts that had progressively increased over the past 30 years. Familial history was unremarkable. Clinical examination revealed a strikingly enlarged abdomen ...