I hope we made it interesting

A Multimedia Constraint System (or: do we have it MADE)

The MADE constraint system provides excellent opportunities to introduce constraints in a multimedia application. Multimedia applications are not only a good place to experiment with constraint systems; constraints in a multimedia environment are almost indispensable. Due to the overwhelming amount of data and the number of relations between several parts of this data, multimedia applications a...

I Know It When I See It: The Challenges of Addressing Corruption in Health Systems; Comment on “We Need to Talk About Corruption in Health Systems”

In this commentary, I argue that corruption in health systems is a critical and legitimate area for research in order to strengthen health policy goals. This rationale is based partly on citizen demand for more accountable and transparent health systems, along with the fact that the poor and vulnerable suffer the most from the presence of corruption in health systems. W...

Round and round we go: sedation -- what is it, who does it, and have we made things safer for children?

In this issue of Pediatric Anesthesia several papers and commentaries authored by anesthesiologists and nonanesthesiologists describe different perspectives regarding sedation ⁄ analgesia for children in the UK and the USA. I will provide historical perspectives from the USA and then examine these reports to see how they compare with current USA practice. I had the good fortune of being the co-...

Selenium and vitamin E: interesting biology and dashed hope.

JNCI | Editorials 283 Prostate cancer is an attractive and appropriate target for chemoprevention because of its incidence, prevalence, and disease-related mortality. The molecular pathogenesis of prostate cancer lends itself to a primary prevention strategy. Several histological lesions have been described, including atypical small acinar proliferation, proliferative inflammatory atrophy, and ...

Are we made of aliens?