منابع مشابه
Targeted drug delivery to treat pain and cerebral hypoxia.
Limited drug penetration is an obstacle that is often encountered in treatment of central nervous system (CNS) diseases including pain and cerebral hypoxia. Over the past several years, biochemical characteristics of the brain (i.e., tight junction protein complexes at brain barrier sites, expression of influx and efflux transporters) have been shown to be directly involved in determining CNS p...
متن کاملLiver Targeted Drug Delivery System
Targeted drug delivery or site-specific drug delivery system has the potential to increase local drug concentrations and thereby increase the effectiveness of the medicines with fewer side effects. Liver diseases especially liver cancer is one of the most prevalent cancers, with a high mortality. Due to high toxicity and poor specificity of the chemotherapeutic agents the present method of trea...
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ژورنال
عنوان ژورنال: Chemical Society Reviews
سال: 2019
ISSN: 0306-0012,1460-4744
DOI: 10.1039/c8cs00304a