منابع مشابه
Dendritic h Channelopathy in Epileptogenesis
Recent work has suggested a link between h channels and epilepsy. In this issue of Neuron, Shah et al. demonstrate that a robust, postseizure decrease in h channels during a critical phase of epileptogenesis mechanistically underlies dendritic hyperexcitability in entorhinal-hippocampal pyramidal cells.
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During the past 20 years, we have witnessed a dramatic increase in our knowledge of the genetic basis of the cardiomyopathies and the primary electrical disorders (‘‘ion channelopathies’’). This review aims to provide an overview of the different genes linked to these disorders to date. Heart Metab. 2008;41:5–10.
متن کاملDendritic ion channelopathy in acquired epilepsy.
Ion channel dysfunction or "channelopathy" is a proven cause of epilepsy in the relatively uncommon genetic epilepsies with Mendelian inheritance. But numerous examples of acquired channelopathy in experimental animal models of epilepsy following brain injury have also been demonstrated. Our understanding of channelopathy has grown due to advances in electrophysiology techniques that have allow...
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http://www.sciencemag.org/cgi/content/full/305/5683/532 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/305/5683/532/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://w...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2005
ISSN: 1535-7597,1535-7511
DOI: 10.1111/j.1535-7511.2005.00073.x