Hypoxemic Bronchiolitis Related to Major Histocompatibility Class II Deficiency
نویسندگان
چکیده
منابع مشابه
Hypoxemic Bronchiolitis Related to Major Histocompatibility Class II Deficiency
Major histocompatibility complex class II expression deficiency is an autosomal recessive primary combined immunodeficiency. The prevalence of this deficiency is the highest in Mediterranean areas, especially North Africa. Early diagnosis is essential due to high mortality in the first 2 years of life. Prognosis is very poor when bone marrow transplantation cannot be performed. We report the ca...
متن کاملFrequency of Major Histocompatibility Antigens Class I in Mazandaran Province
Background and purpose: Major histocompatibility antigens are the most polymorphic components of the immune system. The purpose of this study was to determine the frequency of human leukocyte antigens (HLA) in a population in Mazandaran province, Iran. Materials and methods: In a cross sectional study, peripheral blood samples were obtained from 550 people in Immunogenetics Research Center af...
متن کاملCellular and gene therapy for major histocompatibility complex class II deficiency.
Major histocompatibility complex (MHC) class II deficiency is a primary immunodeficiency. Lentiviral vectors are used for gene therapy in a mouse model of this disease. In addition, by a direct genetic correction approach, a diagnostic test to determine which of the four MHC II genes is defective in new MHC II-deficiency patients has been optimized.
متن کاملClinical course of patients with major histocompatibility complex class II deficiency.
The clinical course of 10 children who have been diagnosed with major histocompatibility complex (MHC) class II deficiency (bare lymphocyte syndrome) in the UK over the past eight years is described. They have had a generally poor prognosis, with only two of the 10 still alive despite eight attempts at bone marrow transplantation in six patients. Overwhelming viral infection was the predominant...
متن کاملMajor histocompatibility complex class II and BTNL2 associations in sarcoidosis.
Infect Dis 2009; 9: 162–172. 4 Li T, Chiang JY. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4a and coactivators, and suppression of small heterodimer partner gene expression. Drug Metab Dispos 2006; 34: 756–764. 5 Handschin C, Meyer UA. Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR. Arch Biochem ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Case Reports in Medicine
سال: 2013
ISSN: 1687-9627,1687-9635
DOI: 10.1155/2013/315073