Hypothalamo-pituitary-adrenocortical (HPA) function in the morphine dependent rat
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چکیده
منابع مشابه
The hypothalamo-pituitary-adrenocortical system.
Control of the secretion of ACTH appears to involve several mechanisms. It is dependent upon the release, from neurones in the hypothalamus, of corticotrophin releasing factor, which is probably a complex including CRF-41 and vasopressin. The secretion of the complex is influenced by various central inhibitory and excitatory nervous pathways. The releasing factor is conveyed by the hypophyseal ...
متن کاملIntroduction to the Hypothalamo- Pituitary-adrenal (hpa) Axis
OBJECTIVES: • Identify appropriate hypothalamic factors that control the secretion of each of the anterior pituitary hormones, and describe their route of transport from the hypothalamus to the anterior pituitary. • Contrast the anterior and posterior pituitary lobes with respect to cell types, vascular supply, development, and innervation (hypothalamic). • Diagram the short-loop and long-loop ...
متن کاملSpinal and supraspinal analgesic effects of Nimodipine : The role of Hypothalamo-Pituitary-Adrenal(HPA) axis .
Nimodipine, an L-type calcium channel blocker, can induce analgesia. However, it is not clear that this analgesic effect is at the level of spinal or supraspinal pain pathway. In addition, it has been reported that the analgesic effect of nifedipine, another L-type calcium channel blocker is related to the HPA axis, but there is no report indicating the role of this axis in the analgesic eff...
متن کاملNeurocircuitry of stress integration: anatomical pathways regulating the hypothalamo-pituitary-adrenocortical axis of the rat.
The hypothalamo-pituitary-adrenocortical (HPA) axis is recruited by the organism in response to real or perceived threats to homeostasis ("stress"). Regulation of this neuroendocrine system is accomplished by modulation of secretory tone in hypophysiotrophic neurons of the medial parvocellular paraventricular nucleus. Excitation of these neurons is mediated by several sources: direct (and perha...
متن کاملLimbic system mechanisms of stress regulation: hypothalamo-pituitary-adrenocortical axis.
Limbic dysfunction and hypothalamo-pituitary-adrenocortical (HPA) axis dysregulation are key features of affective disorders. The following review summarizes our current understanding of the relationship between limbic structures and control of ACTH and glucocorticoid release, focusing on the hippocampus, medial prefrontal cortex and amygdala. In general, the hippocampus and anterior cingulate/...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1979
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.75.215