Hypothalamic Lesions and Disinhibition of Feeding

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VENTROMEDIAL HYPOTHALAMIC NUCLEI AND FEEDING BEHAVIOR

The role of the ventromedial nuclei of the hypothalamus (VMN) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. Electrolytic lesions were induced stereotaxically (1.2 mA, 15 sec). Results revealed a significant decrease (p<O.05) in body weight (BW) and food intake (FI) in the order of lesioned <sham <control during the fIrst week. However, ...

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ventromedial hypothalamic nuclei and feeding behavior

the role of the ventromedial nuclei of the hypothalamus (vmn) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. electrolytic lesions were induced stereotaxically (1.2 ma, 15 sec). results revealed a significant decrease (p

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Lateral Hypothalamic Lesions

Address all correspondence to Dr. George A. Bray. Received for publication 14 February 1983 and in revised form 19 May 1983. INTRODUCTION Following the observation by Hetherington and Ranson (1) that ventromedial hypothalamic lesions were associated with obesity, Anand and Brobeck (2) demonstrated in 1951 that lesions placed more laterally in the hypothalamus were associated with hypophagia or ...

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Combination unilateral amygdaloid and ventromedial hypothalamic lesions: evidence for a feeding pathway.

Previous studies have reported hyperphagia and obesity in female rats with bilateral lesions of the most posterodorsal part of the amygdala. In rats with unilateral posterodorsal amygdaloid lesions, a dense pattern of anterograde degeneration appears in the ipsilateral ventromedial hypothalamus, but not the contralateral nucleus. In the present study, female rats with unilateral ventromedial hy...

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Hypothalamic clocks and rhythms in feeding behaviour.

Daily rhythms are evident across our physiology, ranging from overt behavioural patterns like sleep to intricate molecular rhythms in epigenetic coding. Driving these rhythms at an anatomical and cellular level are circadian clock networks comprising core clock genes and an ever-expanding list of clock-controlled genes. Research over the past decade has revealed an intimate relationship between...

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ژورنال

عنوان ژورنال: Science

سال: 1965

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.150.3701.1322-a