منابع مشابه
Canola oil influence on azoxymethane-induced colon carcinogenesis, hypertriglyceridemia and hyperglycemia in Kunming mice.
Azoxymethane (AOM) is a potent genotoxic carcinogen which specifically induces colon cancer. Hyperlipidemia and diabetes have several influences on colon cancer development, with genetic and environmental exposure aspects. Here, we investigated plasma lipid and glucose concentrations in Kunming mice randomized into four groups; control (no AOM or oil exposure), AOM control, AOM + pork oil, and ...
متن کاملRapid Publications Induction of Hyperinsulinemia Combined With Hyperglycemia and Hypertriglyceridemia Increases Plasminogen Activator Inhibitor
Hypofibrinolysis caused by increased plasminogen activator inhibitor 1 (PAI-1) has been implicated in the vasculopathy of type 2 diabetes, typified by increased insulin, glucose, and triglycerides. However, short-term infusions of insulin have not increased PAI1 in normal subjects. We hypothesized that induction of increased insulin accompanied by increased glucose and triglycerides would incre...
متن کاملHypertriglyceridemia
Hypertriglyceridemia (HTG) is commonly encountered in lipid and cardiology clinics. Severe HTG warrants treatment because of the associated increased risk of acute pancreatitis. However, the need to treat, and the correct treatment approach for patients with mild to moderate HTG are issues for ongoing evaluation. In the past, it was felt that triglyceride does not directly contribute to develop...
متن کاملApolipoprotein A5 and hypertriglyceridemia.
Hypertriglyceridemia is associated with increased risk of coronary heart disease (CHD) (1–5), and it is an integral component of the overlapping syndromes of familial combined hyperlipidemia, insulin resistance syndrome, atherogenic lipoprotein profile, and hyperapobetalipoproteinemia (6 ). More than one mechanism may be involved in the increased risk of CHD associated with increased serum trig...
متن کاملPancreatitis Induced by Hypertriglyceridemia
The detailed pathophysiological mechanisms involved in the progression of hypertriglyceridemia to pancreatitis are little known. Using an animal model we have found that the earliest detectable changes caused by hypertriglyceridemia consist of a selective degeneration of the mitochondria in the exocrine pancreas cells. This supports the view that an excess of free fatty acids deranges the mitoc...
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ژورنال
عنوان ژورنال: Journal of Metabolic Syndrome
سال: 2015
ISSN: 2167-0943
DOI: 10.4172/2167-0943.1000i101