Hyperthyrotrophinaemia during thyroxine replacement therapy.

Hyperthyrotrophinaemia during thyroxine replacement therapy.

During the follow-up of 224 cases of treated hypothyroidism, 14 clinically euthyroid patients were found to have elevated serum thyrotrophin and normal total thyroxine concentrations. Closer observation of these patients during the following 27 months resulted in the serum thyrotrophin levels returning to normal spontaneously in 8 patients (Group 1) whilst remaining elevated in 6 (Group 2), des...

Thyroxine replacement therapy: prescribing patterns

This work was supported by grants from the Medical Research Council, the North of England Cancer Campaign, the Wellcome Trust, the League of Friends of the Royal Victoria Infirmary, the Ernest and Minnie Dawson Cancer Trust, the research committee, Newcastle Area Health Authority (Teaching), and the Welsh Office Scheme for Development of Health and Social Research. We are most grateful to Miss ...

Thyroxine alone or thyroxine plus triiodothyronine replacement therapy for hypothyroidism.

Standard therapy for patients with hypothyroidism is replacement with synthetic thyroxine (T4). However, thyroxine plus triiodothyronine (T3) replacement therapy resulted in marked improvements in several items of the Profile of Mood States and in a few indices of psychometric function and quality of life. The adequacy of thyroxine alone versus thyroxine plus triiodothyronine to treat hypothyro...

[Nicotine replacement therapy during pregnancy].

In spite of the fact that smoking is the main cause of obstetric morbidity and mortality, 20% of North American women smoke during pregnancy. In Spain, this figure is as high as 30% to 35%. Treating smoking addiction in these patients should be the first and most important therapeutic measure undertaken by health professionals responsible for the care of pregnant women. All experts recommend th...

hepatitis b infection during renal replacement therapy