Hypersensitivity reactions to drugs in acquired immunodeficiency syndrome.

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Hypersensitivity reactions to drugs in acquired immunodeficiency syndrome.

We describe a patient with AIDS in whom recurrent drug eruption and fever following administration of various unrelated agents developed. Previous drug exposure was uneventful. A possible mechanism for this phenomenon is described.

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Strictly speaking, biological drugs are defined as drugs obtained using biotechnology that act on the immune system. They encompass monoclonal antibodies, fusion proteins, and cytokines. Although they are restricted to specific diseases, they have been increasingly used in recent years, with the consequent reporting of adverse reactions, many of which occur during the postmarketing phase. Becau...

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Rapid desensitization for hypersensitivity reactions to chemotherapeutic drugs; a case series

Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...

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Rapid desensitization for hypersensitivity reactions to chemotherapeutic drugs; a case series

Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1987

ISSN: 0032-5473

DOI: 10.1136/pgmj.63.735.55