Hyperphosphatemia and phosphate binders: effectiveness and safety
نویسندگان
چکیده
منابع مشابه
Effectiveness and cost-efficiency of phosphate binders in hemodialysis
HEALTH POLITICAL BACKGROUND In 2006, the prevalence of chronic renal insufficiency in Germany was 91,718, of which 66,508 patients were on dialysis. The tendency is clearly growing. SCIENTIFIC BACKGROUND Chronic renal insufficiency results in a disturbance of the mineral balance. It leads to hyperphosphataemia, which is the strongest independent risk factor for mortality in renal patients. Us...
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1. Simeone DM, Sandelin K, Thompson NW. Undescended superior parathyroid gland: a potential cause of failed cervical exploration for hyperparathyroidism. Surgery 1995; 118: 949–956 2. Manley NR, Selleri L, Brendolan A et al. Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol 2004; 276: 301–312 3. Billingsley KG, Douglas LF, Doppman J...
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The use of an oral phosphate binder is a promising and most practical strategy for the prevention of vascular calcification in patients with chronic kidney disease (CKD). To secure the safety: 1) the oral phosphate binder must not cause adverse effects in the gastrointestinal tract; 2) the oral phosphate binder should be non-absorbable or barely absorbable through the gastrointestinal tract, or...
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Increased cardiovascular morbidity and mortality has been associated with the hyperphosphatemia seen in patients with end-stage chronic kidney disease (CKD). Oral phosphate binders are prescribed in these patients to prevent intestinal absorption of dietary phosphate and reduce serum phosphate. In prospective observational cohorts they have shown to decrease all-cause and cardiovascular mortali...
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ژورنال
عنوان ژورنال: Current Medical Research and Opinion
سال: 2013
ISSN: 0300-7995,1473-4877
DOI: 10.1185/03007995.2013.841667