Hyperleukocytosis: Emergency Management : Correspondence

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Leukapheresis in management of hyperleukocytosis in children's leukemias.

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Spurious Hyperleukocytosis

Hyperleukocytosis is an oncological emergency but is extremely rare in non-malignant conditions. Nucleated RBCs give rise to spuriously high total leucocyte count and cause clinical dilemma. Thalassemia major patients are known to have leucocytosis even after correction for nucleated RBCs. We report a case of undiagnosed Thalassemia major in a 4 month old infant with total leucocyte count highe...

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Emergency Management of Common Diseases in Children

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Hypoxemia During Extreme Hyperleukocytosis: How Spurious?

BACKGROUND Spurious hypoxemia has been described in case reports during extreme hyperleukocytosis and has led to recommendations for immediate cooling and analysis of arterial blood gases (ABGs). We sought to determine, in samples processed as recommended, the magnitude of spurious hypoxemia in acute leukemia subjects with hyperleukocytosis. METHODS A retrospective chart review was conducted ...

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ژورنال

عنوان ژورنال: The Indian Journal of Pediatrics

سال: 2013

ISSN: 0019-5456,0973-7693

DOI: 10.1007/s12098-013-1081-0