Hyperdynamic circulatory syndrome in a mouse model transgenic for SerpinB3
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چکیده
منابع مشابه
P-111: An Attempt to Facilitate the Production of Transgenic Mouse As A Model for Gene Therapy of Gaucher Disease
Background: Gaucher disease is an autosomal recessive inherited lysosomal storage disorder that affects many of the body's organs and tissues by defective function of the catabolic enzyme β-glucocerebrosidase. Gene therapy is one of the efficient ways for treatment of this disease. Due to the lack of appropriate animal models, in the field of gene therapy little progress has been done.Mate...
متن کاملCORRIGENDUM: SERPINB3 is associated with longer survival in transgenic mice
Marika Crescenzi was omitted from the author list in the original version of this Article. This has been corrected in the PDF and HTML versions of the Article. The Author Contributions section should read ‘‘G.V. designed and performed the experiments, analyzed data and drafted the manuscript, M.R., G.C., C.T., A.C. preformed molecular biology experiments, S.Q., A.B. performed cell culture andwe...
متن کاملSERPINB3 is associated with longer survival in transgenic mice
The physiological roles of the protease inhibitor SERPINB3 (SB3) are still largely unknown. The study was addressed to assess the biological effects of this serpin in vivo using a SB3 transgenic mouse model. Two colonies of mice (123 transgenic for SB3 and 148 C57BL/6J controls) have been studied. Transgenic (TG) mice showed longer survival than controls and the difference was more remarkable i...
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چکیده ندارد.
A transgenic mouse model for studying HBV infection in neonate
The human hepatitis B virus (HBV) infection is always a worldwide problem, especially the high risk infection of the neonate by chronically HBV infected mother. McGrane et al. [1] have demonstrated that the gene which is driven by the promoter of phosphoenolpyruvate carboxykinase (PEPCK) is mainly expressed in the mouse liver and immediately appears at parturition. We have constructed a transge...
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ژورنال
عنوان ژورنال: Annals of Hepatology
سال: 2020
ISSN: 1665-2681
DOI: 10.1016/j.aohep.2019.06.021