Hypercoagulability in Dogs with Blastomycosis

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Hypercoagulability in Dogs with Blastomycosis

BACKGROUND Blastomycosis is a potentially fatal fungal disease that most commonly affects humans and dogs. The organism causes systemic inflammation and has a predilection for the lungs. The inflammation might lead to a hypercoagulable state with microemboli in the pulmonary circulation which could contribute to inadequate oxygen exchange in infected dogs. HYPOTHESIS/OBJECTIVES Dogs with blas...

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Hypercoagulability is a state in which the hemostatic balance shifts toward excessive platelet activation and fibrin deposition, leading to thrombosis. Although a definitive diagnosis is often difficult to make, identifying patients at risk for thromboembolism is critical. By identifying these patients and understanding mechanisms that contribute to hypercoagulability, clinicians can select pro...

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Treatment of blastomycosis with itraconazole in 112 dogs.

One hundred twelve client-owned dogs with blastomycosis were treated with itraconazole, 5 or 10 mg/kg/d. The first group of 70 dogs treated in 1987 and 1988 received 10 mg/kg/d (group 1), and the second group of 42 dogs treated after October 1988 received 5 mg/kg/d (group 2). Even though the groups were treated at different times, the dogs were similar in age and gender distribution, number of ...

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ژورنال

عنوان ژورنال: Journal of Veterinary Internal Medicine

سال: 2015

ISSN: 0891-6640

DOI: 10.1111/jvim.12538