Hypercalcaemia, Hypophosphataemia, and Inability to Excrete Hydrogen Ions
نویسندگان
چکیده
منابع مشابه
Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized in man by parathyroid, pancreatic, pituitary and adrenal tumours. The MEN1 gene encodes a 610-amino acid protein (menin) which is a tumour suppressor. To investigate the in vivo role of menin, we developed a mouse model, by deleting Men1 exons 1 and 2 and investigated this for MEN1-associated tumours and ...
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School of Medicine and Pharmacology, Royal Perth Hospital, University of Western Australia, Perth, WA, Australia Department of Clinical Biochemistry, PathWest Laboratory Medicine, Royal Perth Hospital, Perth, WA, Australia Kolling Institute Royal North Shore Hospital, St Leonards, NSW, Australia Correspondence to: P Glendenning, Department of Clinical Biochemistry, PathWest Laboratory Medicine,...
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ژورنال
عنوان ژورنال: BMJ
سال: 1972
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5837.400