Hydroxymethylglutaryl coenzyme a reductase inhibitors down-regulate chemokines and chemokine receptors in patients with coronary artery disease
نویسندگان
چکیده
منابع مشابه
Coronary Artery Disease and Atherosclerosis Hydroxymethylglutaryl Coenzyme A Reductase Inhibitors Down-Regulate Chemokines and Chemokine Receptors in Patients With Coronary Artery Disease
OBJECTIVES We sought to investigate whether the activation of the chemokine network observed in patients with coronary artery disease (CAD) could be modified by treatment with 3-hydroxy3-methylglutaryl coenzyme A reductase inhibitors (statins). BACKGROUND Chemokines and chemokine receptors are important mediators in atherogenesis, and we hypothesized that the statins could affect the chemokine ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2003
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(03)00263-8