Hydroxychloroquine-induced Pruritus

Hydroxychloroquine-induced pruritus.

Sir, Hydroxychloroquine is a derivative of chloroquine and is frequently used in dermatological practice in the management of a number of conditions including photosensitivity disorders. There are a number of recorded side-e¡ects of this therapy. Pruritus is a well recognized side-e¡ect of chloroquine treatment of malaria in Africans and has also, rarely, been reported in Caucasians. To our kno...

Hydroxychloroquine Induced Retinopathy: A Case Series

Background and Purpose: Occular toxicity is one of the most important complications of Hydroxychloroquine. Not any type of treatment has so far been found and recommended for this disorder. The purpose of this study was to report some characteristics of patients with Hydroxychloroquine Induced Retinopathy.    Materials and Methods: From 107 patients with rheumatoid arthritis (...

Hydroxychloroquine and colchicine induced myopathy.

Chloroquine-induced Pruritus

Chloroquine-induced pruritus remains one of the most common side-effects in the use of chloroquine in the prophylaxis and treatment of uncomplicated malaria before the advent of artemisinin-based combination therapies. It has been reported to vary from a tolerable to intolerable intensity among susceptible individuals resulting in disruption of treatment and development of resistance to the dru...

Drug-induced pruritus: a review.

Pruritus is an unpleasant sensation that leads to scratching. In addition to several diseases, the administration of drugs may induce pruritus. It is estimated that pruritus accounts for approximately 5% of all skin adverse reactions after drug intake. However, to date there has been no systematic review of the natural course and possible underlying mechanisms of drug-induced pruritus. For exam...