Hydrolytic and Nonenzymatic Functions of Acetylcholinesterase Comodulate Hemopoietic Stress Responses

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses.

Glucocorticoid-initiated granulocytosis, excessive proliferation of granulocytes, persists after cortisol levels are lowered, suggesting the involvement of additional stress mediator(s). In this study, we report that the stress-induced acetylcholinesterase variant, AChE-R, and its cleavable, cell-penetrating C-terminal peptide, ARP, facilitate granulocytosis. In postdelivery patients, AChE-R-ex...

متن کامل

Nonenzymatic Functions of Acetylcholinesterase Splice Variants in the Developmental Neurotoxicity of Organophosphates: Chlorpyrifos, Chlorpyrifos Oxon, and Diazinon

BACKGROUND Organophosphate pesticides affect mammalian brain development through mechanisms separable from the inhibition of acetylcholinesterase (AChE) enzymatic activity and resultant cholinergic hyperstimulation. In the brain, AChE has two catalytically similar splice variants with distinct functions in development and repair. The rare, read-through isoform, AChE-R, is preferentially induced...

متن کامل

a contrastive study of rhetorical functions of citation in iranian and international elt scopus journals

writing an academic article requires the researchers to provide support for their works by learning how to cite the works of others. various studies regarding the analysis of citation in m.a theses have been done, while little work has been done on comparison of citations among elt scopus journal articles, and so the dearth of research in this area demands for further investigation into citatio...

MicroRNA functions in stress responses.

MicroRNAs (miRNAs) are a class of ∼22 nucleotide short noncoding RNAs that play key roles in fundamental cellular processes, including how cells respond to changes in environment or, broadly defined, stresses. Responding to stresses, cells either choose to restore or reprogram their gene expression patterns. This decision is partly mediated by miRNA functions, in particular by modulating the am...

متن کامل

Non-cholinergic functions of acetylcholinesterase.

24 Schalk, I., Ehret-Sabatier, I,., Houet, F., Goeldner, M. and Hirth, C. (1994) Eur. J. Hiochem. 219, 155-159 2.5 Harel, M., Sussman, J. I,., Krejci, E.> Hon, S., Chanal. P., Massoulie, J. and Silman. I. (1992) Proc. Natl. Acad. Sci. LJSA. 89, 108271083 1 26 Eichler, J.. Anselmet, A,, Sussman, J. I,.. Massoulie, J. and Silman, 1. (1994) Mol. Pharmacol. 45, 335-340 27 Kadic, Z.. I’ickering, N.,...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Journal of Immunology

سال: 2005

ISSN: 0022-1767,1550-6606

DOI: 10.4049/jimmunol.176.1.27