منابع مشابه
Enzymic hydrolysis of sphingomyelin in the presence of bile salts.
Sphingomyelin in mixed dispersion with bile salts was hydrolysed by the solubilized sphingomyelinase of rat brain lysosomes. In parallel studies, physical properties of these dispersions were determined. The kinetic curves that described the rate of hydrolysis as a function of increasing concentrations of bile salt were multiphasic. A region of very low activity was followed by an ascending por...
متن کاملHydrolysis of milk fat globules by pancreatic lipase. Role of colipase, phospholipase A2, and bile salts.
Human milk fat globules require colipase to be hydrolyzed by pancreatic lipase in the presence of bile salts. This is contrary to a recent report in this Journal (J. Clin. Invest. 67: 1748-1752.) according to which inhibition of lipase by bile salt could be overcome by the addition of colipase or phospholipase A2. This latter finding is shown to be due to contamination of commercially available...
متن کاملAsystole after alfentanil- succinylcholine
To the Editor: Alfentanil is a new narcotic capable of blunting intraoperalive haemodynamic responses while allowing for return of spontaneous ventilation and consciousness after short surgical procedures. We have recently noted reports of severe bradycardia with the use of alfentanil combined with succinylcholine, t,2 We also present such a case. A 76-year-old 45 kg woman was scheduled for rem...
متن کاملOptimal dose of succinylcholine revisited.
BACKGROUND The authors reappraised the conventional wisdom that the intubating dose of succinylcholine must be 1.0 mg/kg and attempted to define the lower range of succinylcholine doses that provide acceptable intubation conditions in 95% of patients within 60 s. METHODS This prospective, randomized, double-blind study involved 200 patients. Anesthesia was induced with 2 mug/kg fentanyl and 2...
متن کاملThe right dose of succinylcholine.
SUCCINYLCHOLINE is considered to be endowed with two great qualities: It provides intense paralysis rapidly, and its effect is likely to wear off before an adequately preoxygenated patient becomes hypoxic. However, this claim was challenged because calculations showed that at the recommended dose, 1 mg/kg, preoxygenated patients were likely to become hypoxic before spontaneous breathing resumed...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1954
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1954.tb00857.x