Hydro-Mechanical Neonatal Encephalopathy (HNE): An Alternative Hypothesis

Neonatal encephalopathy in foals.

Neonatal encephalopathy is a common central nervous system disorder of neonatal foals and human infants, resulting in clinical signs such as lethargy, inappropriate behavior, seizures, and other neurologic deficits. Although neonatal encephalopathy is frequently seen in equine practice, a paucity of veterinary clinical and basic science research data is available. Therefore, the pathophysiologi...

An Elastoplastic Hydro-mechanical Model for Unsaturated Soils

This paper presents a coupled elastoplastic constitutive model for predicting the hydraulic and stress-strain-strength behaviour of unsaturated soils. Hydraulic hysteresis in the water-retention behaviour is modeled as an elastoplastic process with the elastic region of the saturation degree. The effect of change in degree of saturation on the stress-strain-strength behaviour and the effect of ...

From falsification to generating an alternative hypothesis

An alternative to null-hypothesis significance tests.

The statistic p(rep) estimates the probability of replicating an effect. It captures traditional publication criteria for signal-to-noise ratio, while avoiding parametric inference and the resulting Bayesian dilemma. In concert with effect size and replication intervals, p(rep) provides all of the information now used in evaluating research, while avoiding many of the pitfalls of traditional st...

Cerebral palsy and neonatal encephalopathy.

A retrospective cohort study was carried out to test the hypothesis that children born at term with cerebral palsy with signs of neurological dysfunction preceded by depression at birth (termed neonatal encephalopathy) differ from those without such signs in the frequency of antenatal and perinatal factors, and in the severity and characteristics of their impairment and disability. The study wa...