Hydralazine therapy in idiopathic sle

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Orogenital ulcers, SLE and hydralazine.

The case is reported of a man developing drug-induced systemic lupus erythematosus while taking hydralazine. The illness was characterized by arthritis and a purpuric rash particularly in the light-sensitive areas as well as orogenital and cutaneous ulceration. Anti-nuclear antibody and DNA binding were positive. All clinical manifestations disappeared on withdrawal of hydralazine.

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Idiopathic Thrombocytopenic Purpura Masquerading Paediatric SLE

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Oral hydralazine therapy for chronic refractory heart failure.

The hemodynamic effects of oral hydralazine were investigated in ten patients (nine in NYHA Class IV and one in Class III) with chronic refractory heart failure. With hemodynamic monitoring, adequate oral doses of hydralazine (50 or 75 mg) were determined and then administered every six hours. Hemodynamics were determined at 2-3, 6-8 and 24 hours on hydralazine therapy. Arterial pressure decrea...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 1976

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.1780190124