Hybrid Methods of Desktop Journal Article Delivery

Journal Article

Four lines of evidence support a central role for H. pylori and PUD: (1) the natural history of H. pylori infection, (2) epidemiologic data, (3) outcomes after cure of H. pylori infection in patients with PUD, and (4) the frequent development of gastric ulcers in H. pylori-infected Mongolian gerbils. With so much circumstantial evidence and with Koch's postulates arguably fulfilled for a direct...

Journal Article

Journal Article

It is now recognized that there is a two-way interaction between Helicobacter pylori gastritis and gastric physiology. H. pylori gastritis can alter gastric physiology, leading to increased or decreased acid secretion depending on the pattern of gastritis present. These changes in physiology are related to the disease outcome, with increased acid secretion leading to duodenal ulcer disease and ...

Journal Article

During the past 20 years, endoscopy has developed as the modality of choice for determining diagnosis, prognosis, and therapy for severe gastrointestinal bleeding. When endoscopy was first introduced to evaluate gastrointestinal bleeding in the late 1970s, early diagnostic endoscopy did not affect patient outcome. [46] Subsequently, improvements in endoscopes and endoscopic accessories allowed ...

Journal Article

Helicobacter pylori may be the world's commonest chronic infection. Estimates suggest that more than half the world's population is infected by this gastric bacterium. Since the discovery and successful culture of H. pylori in the 1980s, it has become clear that the infection is important in the initiation of gastritis, resulting in numerous manifestations of gastroduodenal disease. Clinical ou...