منابع مشابه
Dmd056945 1964..1970
The organic anion-transporting polypeptide (OATP) 1B3 is a membrane transport protein that mediates hepatic uptake of many drugs and endogenous compounds. Currently, determination of OATP-mediated drug-drug interactions in vitro is focused primarily on direct substrate inhibition. Indirect inhibition of OATP1B3 activity is under-appreciated. OATP1B3 has putative protein kinase C (PKC) phosphory...
متن کاملAlejandro Sánchez Alvarado (1964- )
Alejandro Sánchez Alvarado is a Professor of Neurobiology and Anatomy at the University of Utah School of Medicine and is also a Howard Hughes Medical Institute [4] Investigator. Born in Caracas, Venezuela, 24 February 1964, Sánchez Alvarado left his home to pursue education in the United States, where he received a Bachelor of Science in molecular biology and chemistry from Vanderbilt Universi...
متن کاملDmd058347 1873..1880
Historically, since the metabolism of administered peptide/protein drugs (“biotherapeutics”) has been expected to undergo predictable pathways similar to endogenous proteins, comprehensive biotherapeutic metabolism studies have not been widely reported in the literature. However, since biotherapeutics have rapidly evolved into an impressive array of eclectic modalities, there has been a shift t...
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ژورنال
عنوان ژورنال: Atatürk Araştırma Merkezi Dergisi
سال: 2020
ISSN: 1011-727X
DOI: 10.33419/aamd.702817