Humoral and cellular immune responses to glucose regulated protein 78 - a novel Leishmania donovani antigen
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چکیده
منابع مشابه
Humoral immune responses to cathepsin D and glucose-regulated protein 78 in ovarian cancer patients.
Many cancer patients develop tumor-reactive immune responses against antigens that are either expressed on the surface of tumor cells or released from them into the peripheral circulation. In this study, tumor-reactive immunoglobulins, present in the sera of ovarian cancer patients, were used to identify commonly recognized tumor-associated antigens on ovarian tumor cells. Western immunoblot an...
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متن کاملtherapeutic potential of glucose regulated protein 78 in cancer
endoplasmic reticulum has a critical role in the synthesis and folding of secretory and membrane proteins. high accumulation of proteins in er activates the unfolded protein response and glucose regulated protein 78 or gpr78 plays an essential role in this pathway. unfolded protein response is activated in cancerous cells due to their adverse condition to survive and it has been shown that grp...
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ژورنال
عنوان ژورنال: Tropical Medicine and International Health
سال: 2002
ISSN: 1360-2276,1365-3156
DOI: 10.1046/j.1365-3156.2002.00880.x