Human Subject with Unexpected Biodistribution of [11C]PK11195

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Human Subject with Unexpected Biodistribution of [ 11 C ] PK 11195

[N-Methyl11 C](R)-1-(2-chlorophenyl)-N-(1-methylpropyl)-3-isoquinoline carboxamide [ 11 C]PK11195 is a widely used radiopharmaceutical for in vivo assessment of translocator protein 18 kDa (TSPO) activity using positron emission tomography. Here we present an interesting case of unusual distribution of [ 11 C]PK11195, that is a lack of uptake in tissues known for high expression of the TSPO.

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ژورنال

عنوان ژورنال: The Open Nuclear Medicine Journal

سال: 2011

ISSN: 1876-388X

DOI: 10.2174/1876388x01103010010